Clinical & Scientific Framework

The clinical rationale for perioperative preparation.

PERIOME's Clinical & Scientific Framework documents the five physiologic domains of surgical stress, the evidence basis for each ingredient decision, and the formulation principles that distinguish a perioperative protocol from a general wellness supplement. Designed to be reviewed by the clinicians who will recommend it.

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01 / Formulation Architecture

Formulation Architecture

Five physiologic domains, ingredient selection criteria, activated-form rationale, and dosing philosophy for the perioperative window.

02 / Evidence Basis

Evidence Basis

Published RCT and mechanistic literature supporting each domain, with citations and ERAS alignment notes.

03 / Notable Exclusions

Notable Exclusions

Clinical rationale for omitting omega-3s, curcumin, high-dose vitamin E, melatonin, and apigenin from the perioperative formulation.

04 / Manufacturing Standards

Manufacturing Standards

FDA-registered facility, cGMP certification, identity/potency/purity testing protocols, and provisional patent documentation.