Prepare for Surgery | PERIOME PROTOCOL
For Patients

You have a surgery date.Now prepare for it.

The instructions you received tell you when to stop eating and what not to take. They don't tell you what your body actually needs in the days before and after the operating room.

PERIOME was built by anesthesiologists who have been at the head of the bed for thousands of surgeries — and who know exactly what a physiologically prepared patient looks like compared to one who wasn't. This protocol is what they wish every patient had access to before walking in.

Join the waitlist →
Morton™ · Patient companion · In development
The Perioperative Window

There are weeks between your surgery date and the operating room. Medicine has never given you a plan for them.

Your surgeon prepared for your procedure. Your anesthesiologist prepared the medications. The operating room was ready.

No one prepared your body.

Not because it doesn't matter — it matters enormously. Because no one had built the clinical infrastructure to do it. Until now.

What Surgery Demands

Surgery challenges your body across six dimensions simultaneously. Most patients enter it unprepared for any of them.

← scroll to explore

01
Your brain needs support at induction.

Anxiety, sleep disruption, and fasting combine to alter your neurocognitive baseline before anesthesia begins. How clearly you emerge from surgery is partly determined by how ready your brain was going in.

02
Your muscles begin breaking down before the incision.

The fasting period before surgery depletes your cellular fuel reserves. By the time you arrive at the hospital, your body has already shifted into a catabolic state — breaking down muscle to meet its energy needs.

03
Your fluid balance is already off.

Most surgical patients arrive dehydrated. Not severely — but meaningfully. IV fluids during surgery address what's happening in the moment. They don't correct the days before.

04
Your gut is about to be disrupted.

Anesthesia, antibiotics, and surgical stress simultaneously challenge your gut lining and microbiome at the exact moment when your body needs to absorb nutrients for recovery. This is why so many patients feel worse after surgery than they expected.

05
Your immune system is about to be tested.

Surgery triggers an inflammatory response. Whether your body has the nutritional reserves to manage that response — and recover from it — depends on what was present before you went in.

06
Recovery starts before surgery. Not after.

The research is consistent: patients who enter surgery physiologically prepared recover faster, experience fewer complications, and report better outcomes. Preparation is not a wellness concept. It is a clinical variable.

PERIOME Protocol

Seven days before. Seven days after.

PERIOME PROTOCOL is a structured perioperative preparation program — taken once daily, beginning one week before your surgery and continuing through the week after.

← PrepareSurgery DayRecover →
Day −7Day 0Day +7

It was not designed for general wellness. It was designed for the specific physiologic demands of what surgery asks of the human body, based on the same evidence base that informs anesthesia and perioperative medicine.

Once daily. Designed to work around your NPO instructions. No prescription required.

The protocol addresses six evidence-grounded perioperative domains: hydration and electrolyte balance, metabolic and recovery capacity, neurocognitive resilience, immune and inflammatory resilience, GI integrity and microbiome, and micronutrient foundation. Each was selected for a specific perioperative mechanism. Nothing in this formulation is general wellness.

The Perioperative Window

The window opens at scheduling. It closes smarter than it opened.

What's in the Box

Product imagery launching with general availability — 2026.

Physician-Designed

Designed by the physicians who stand at the head of the bed.

PERIOME was co-founded by two board-certified anesthesiologists who have collectively been present for thousands of surgical cases. They have seen what a prepared patient looks like at induction. They have seen what an unprepared one looks like. They built PERIOME because the gap was real, the science to address it existed, and no one had turned it into something patients could actually use.

This is that thing.

Perioperative Resilience Index™ · In development

Readiness is not fixed. It can be moved.

The physiology you bring into surgery is the most modifiable variable in your surgical course. The PRI, in development, is designed to make that visible: from partial toward ready.

Before preparationAfter the protocol
54/ 100
Partially ready
Start · 54
Not readyPartialReadyOptimal

Illustrative. The Perioperative Resilience Index™ is in development. As a patient completes the protocol, readiness is designed to move from partial toward ready.

Meet Morton™ · In development

Soon, a companion for every day of the window.

Morton™ is PERIOME’s perioperative intelligence patient companion. It will turn your protocol into a daily plan, track your readiness, and keep the people preparing you in the loop. Here is a preview of what is coming.

Before surgery · Day −3
After surgery · Day +4
01

Your protocol becomes a plan

Every step, timed to your surgery date, with reminders, streaks, and a clear view of exactly what to do today.

02

Readiness you can watch

Your Perioperative Resilience Index™ updates as you prepare, then recovery signals continue through the full post-operative window.

03

Connected to your care team

Adherence and early physiologic signals route to the clinicians preparing you, so nothing slips between visits.

Illustrative preview. Morton™ is in development.

Get Early Access

PERIOME PROTOCOL is available directly — no referral or surgical program required.

Join to get started. PERIOME PROTOCOL ships directly to you — no surgical program enrollment, no clinical referral. Designed by anesthesiologists, available to every patient with a surgery date who wants to enter the operating room prepared and come out stronger.

Launching 2026 · No commitment required

You're on the list. We'll be in touch.

Part of a PERIOME clinical program? Your care team can coordinate your access directly.

FDA-Registered Facility cGMP-Certified Single-Dose Packets DSHEA-Compliant
Common Questions

What patients ask us.

PERIOME PROTOCOL was formulated by anesthesiologists with drug-nutrient interactions explicitly in mind. Every compound was evaluated against standard perioperative medications — including anesthetic agents, anticoagulants, and antibiotics. No interactions have been identified at the doses formulated. As with any supplement, share your full medication list with your surgical team — they know the specifics of your case.
Any surgery requiring anesthesia. Whether it's orthopedic, general surgical, gynecologic, cardiac, or urologic — the core physiologic demands of fasting, anesthetic exposure, surgical stress, and recovery are consistent across procedure types. PERIOME addresses those shared demands.
No prescription is required. PERIOME is a dietary supplement designed to be physician-recommended, not physician-prescribed. Your care team doesn't need to initiate it — but we encourage you to share the protocol details with your surgeon or anesthesiologist so they can review it in the context of your specific case.
PERIOME is in final launch preparation. Join the waitlist to receive early access and to be notified when availability opens in your area.
PERIOME PROTOCOL is designed to qualify as HSA/FSA eligible. Confirm eligibility with your plan administrator. Insurance reimbursement remains a longer-term goal as clinical outcomes data is established.