Surgery is optimized. The patient entering it is not.
Cleared is not the same as ready.
PERIOME is the clinical infrastructure for surgical readiness and recovery. We help health systems prepare patients better, run safer cases, and deliver measurably better outcomes — across the perioperative window.
Optimize Readiness & Recovery · Demonstrate Value at Scale · Reduce Complications
Readiness distribution · this week
Upcoming cases
Illustrative preview. The PERIOME OS institutional surface is in development; institution, patients, and data shown are illustrative.
Under TEAM, the patient is the financial exposure.
The Transforming Episode Accountability Model went live January 2026 — the first mandatory CMS bundled-payment program built around the full 30-day surgical episode. The proposed CJR-X expansion is positioned to extend the model nationwide. Across the 188 markets participating, the patient who arrives physiologically underprepared is no longer a clinical externality. They are an episode-level financial event. PERIOME is the perioperative preparation infrastructure built for this reimbursement model.
Source: CMS TEAM Model fact sheet (cms.gov).
When the institution owns the whole episode, patient readiness is the difference between a penalty and a bonus.
The cost driver inside every bundle is the complication — and complications track with the one variable the system has never systematically prepared: the patient’s physiology entering surgery, and the visibility of recovery after discharge.
Sources: PMC8558000 · PMC10508298 · PMC10354976 · MDPI J Clin Med 2025.
One avoided readmission in a TEAM-covered joint replacement episode: $15,000–$25,000 in recovered cost. One avoided day-of-surgery cancellation: $5,000–$15,000 in recovered facility revenue. PERIOME OS will make this math visible, attributable, and reportable for every case.
If PERIOME prevents one readmission per 100 surgical cases, the program investment pays for itself. If it prevents two, the return exceeds 10x.
Every dollar of avoided complication is a dollar the bundle lets the institution keep.
The data has been documenting this gap for decades. The infrastructure to close it didn't exist.
Post-operative complications, recovery variability, and extended PACU stays are not random. They are downstream of physiologic conditions that were addressable before the patient reached the OR. PERIOME is the comprehensive clinical infrastructure to address that upstream gap.
PONV is the most common post-anesthetic complaint. It extends PACU time, delays discharge, and elevates nursing burden — in a care setting where throughput directly affects program economics.
About one in four patients over 65 experience postoperative cognitive dysfunction in the first week after major non-cardiac surgery, and about one in ten at three months. Cognitive changes after anesthesia affect discharge readiness and family confidence in the case outcome.
Most ERAS protocols define the day of surgery well. The seven-day window before it — when metabolic, hydration, and micronutrient preparation are still possible — remains largely patient-dependent across most surgical programs.
Designed to integrate. Built to generate signal from day one.
The surgical programs that partner with PERIOME are building the standard of perioperative readiness — systematic patient preparation before surgery and structured outcomes intelligence through recovery. PERIOME integrates at the communication points your team already uses and generates structured outcome data from the first patient enrolled.
The integration point is surgical scheduling — the moment the patient enters the perioperative window. No new clinical workflow steps. No inventory. No dispensing.
Patients obtain the protocol directly. Your institution supports the standard while PERIOME handles product fulfillment and patient-facing educational materials.
Every enrolled patient contributes structured perioperative outcome data. PERIOME formats it for your program's reporting needs and, over time, for publication.
Pilots are structured around your surgical specialty mix, case volume, and clinical workflow — not a one-size-fits-all deployment.
The clinical layer beneath the episode.
You coordinate and carry the episode. PERIOME prepares and quantifies the one variable inside it no one has owned — the patient’s physiology entering surgery, and the visibility of recovery after discharge. PERIOME is additive. It embeds beneath episode coordination. It does not replace it.
Scheduling → Pre-Op → Surgery · Day 0 → Discharge → Day 90
The institution carries the episode. PERIOME prepares the variable inside it.
Built to be evaluated by the people who will deploy it.
PERIOME PROTOCOL is a physician-formulated perioperative preparation and recovery program — built by board-certified anesthesiologists who understand that institutional adoption requires clinical credibility, not marketing positioning. Every formulation decision, every claim, and every implementation structure was designed to withstand the review of a medical director, a surgeon, or an institutional committee.
The formulation is organized around six physiologic domains relevant to surgical stress and early recovery: hydration and electrolytes, metabolic and recovery capacity, neurocognitive resilience, immune and inflammatory resilience, GI integrity and microbiome, and micronutrient foundation.
The clinical framework, exclusions, and rationale can be reviewed by surgeons, anesthesiologists, and perioperative leadership in the context of their patient population and care model.
The programs that partner with PERIOME now are not adding a vendor. They are entering a platform that will grow to include physiologic readiness scoring, genomic precision, and a longitudinal outcomes dataset built on their own patient population. The institutions that build this infrastructure early are positioning themselves ahead of where the standard of care is moving — and helping to determine what that standard becomes.
The protocol is the foundation. PERIOME is building the six-layer perioperative intelligence platform — from nutritional preparation through genomic profiling, readiness scoring, recovery monitoring, and institutional outcomes intelligence. Each layer compounds the value of the one before it. By Layer 6, PERIOME is not a contract line item. It is part of how the program measures and improves its own surgical outcomes. The programs that deploy now are the ones that will define what the standard becomes.
A strategic partnership, not a vendor relationship.
The programs that partner with PERIOME are not adopting a product — they are contributing to the evidence base that will define the standard of perioperative preparation. We work directly with surgical leadership to design implementation, structure outcome measurement, and build the clinical record the category requires. PERIOME is not a vendor. It is an infrastructure partner.
Direct collaboration on where PERIOME belongs in your pathway, how patients are introduced to it, and how it aligns with the communication structure your team already uses.
Clear educational language and protocol structure that helps patients understand when to begin, how to use the protocol, and how it fits with the instructions they already receive from your team.
PERIOME is positioned as a perioperative health company, not as a consumer supplement brand. That makes it easier to evaluate, discuss, and introduce inside serious surgical programs.
Pilots that generate evidence, not just adoption.
The programs that pilot PERIOME are contributing to something larger than a product evaluation — they are building the outcomes dataset that will define what structured perioperative preparation looks like. We design every pilot to generate publishable signal.
ASA physical status I–III surgical patients. Elective and semi-elective procedures. Program determines scope; we support the clinical selection criteria.
Structured data collection across the pre-operative and post-operative window. Timeline and review cadence designed around your program's volume and reporting requirements.
Defined at program onboarding around the metrics your team and medical director care about most. PERIOME structures data collection to generate signal that is meaningful to your program — not just to ours.
No inventory. No prescription workflow. Patient-direct fulfillment with institutional co-branding available. Implementation occurs at the pathway communication level.
Pilot conversations underway with surgical programs performing 50,000+ combined annual cases.
The programs that build this dataset now are writing the standard.
Every patient enrolled in a PERIOME pilot generates structured perioperative outcomes data — PONV incidence, PACU dwell time, discharge readiness, protocol adherence, and recovery trajectory. That data belongs to your program. PERIOME structures it for institutional reporting and, over time, for publication.
The programs that build this dataset now are creating the clinical evidence base for perioperative medicine as a recognized discipline. They will be the programs cited in the literature that defines the standard. That is a different kind of institutional advantage than adding a vendor.
Let's start the conversation.
Every inquiry is reviewed personally by the founding team and followed up with a direct conversation tailored to your program — not a sales deck. Pilots are designed around your patient population, surgical specialty mix, and reporting requirements — not a standard template.
Thank you. The founding team will be in touch within two business days.