The operating system of perioperative medicine.
Perioperative medicine has always known what matters — functional reserve, physiologic readiness, recovery capacity. What it has never had is the infrastructure to act on that knowledge systematically, at scale, before every patient and every surgery.
PERIOME is building that infrastructure.
Surgery has an operating room. An anesthesia machine. A surgical robot. A sterile environment built to exacting standards.
It does not have an operating system for the patient.
PERIOME is building it.
Four layers. One compounding system.
Each layer of the PERIOME platform generates independent clinical value. Together, they create an institutional intelligence system that compounds with every patient — progressively more powerful, progressively more difficult to displace.
The clinical entry point. A 14-day physician-formulated protocol structured across the five physiologic domains surgical stress most directly challenges. Seven days of preparation. Seven days of structured recovery.
A composite readiness score synthesized from continuous wearable biometrics, targeted laboratory data, and a targeted pharmacogenetic panel. The first clinical number for surgical readiness.
Pharmacogenomic profiling and malignant hyperthermia safety screening, conducted through certified clinical reference laboratories. Drug metabolism intelligence delivered to the anesthesiologist before the first case.
The data layer that closes the loop between preparation and outcome. Longitudinal patient data that makes every subsequent patient better prepared — and makes PERIOME indispensable to the institution.
Medicine now has a number for surgical readiness.
The PRI synthesizes data across three input tiers into a single, clinically actionable readiness score — calibrated to the specific physiologic demands of the surgical procedure the patient is about to undergo.
It gives the clinician a picture that has never been systematically assembled. It gives the institution a measurement framework for perioperative readiness at the program level. It gives the patient a preparation target.
Wearable-derived baseline physiologic status. Heart rate variability, sleep architecture, activity, and recovery markers tracked in real time across the preparation window.
Pre-operative laboratory values selected for perioperative relevance — nutritional markers, inflammatory baseline, metabolic readiness, hematologic status.
A targeted panel identifying how the patient metabolizes anesthetic and analgesic medications, plus malignant hyperthermia safety screening. Performed once. Referenced for every subsequent surgical encounter.
Three phases. One operating system.
The PERIOME platform activates across the full perioperative arc. Each phase deploys a different layer of the intelligence system — from preparation through induction through recovery — generating data that compounds with every patient.
Optimization begins at scheduling.
The moment surgery is scheduled, every patient enters a structured readiness protocol. Nutritional status is assessed. Physiologic risk is identified. Personalized interventions are assigned — and where indicated, genomic intelligence informs how each patient metabolizes the medications they will receive in the OR.
The clinical team arrives informed.
The patient is already known — their preparation adherence, physiologic status, and individualized risk profile surfaced before induction. Every clinical decision is data-informed. Nothing about this patient is assumed.
Recovery is where data becomes intelligence.
Recovery protocols are personalized and monitored. Outcome data feeds back into the system — refining protocols, building the institutional evidence base, and generating the longitudinal intelligence that improves every patient who follows.
Every patient makes the system more intelligent.
The most valuable thing PERIOME builds is not the protocol. It is the longitudinal dataset the platform generates — patient-level physiologic data, preparation adherence, anesthetic outcomes, and recovery trajectories, aggregated across every patient in every program PERIOME deploys within.
This dataset does not exist anywhere in medicine today. No health system, no EMR, no payer has it. PERIOME is building it — one patient, one surgery, one recovery at a time.
Programs that deploy PERIOME are not just optimizing their patients.
They are building the evidence base that will define perioperative standards of care.
The data belongs to the institution. The intelligence it generates compounds with every case.
Perioperative readiness is no longer a clinical aspiration. It is a financial imperative.
Under episode-based accountability and value-based care contracts, the physiologic readiness of the patient entering surgery is no longer just a clinical variable — it is a financial one. Every preventable complication, readmission, and day of extended recovery represents measurable institutional cost. PERIOME is the infrastructure that addresses those outcomes at the source.
Readmissions. Complications. Length of stay. Recovery trajectory.
These are the metrics surgical programs are accountable for. They are also the metrics PERIOME is built to move — by addressing the most modifiable variable in surgical outcomes before the patient reaches the OR.
Every deployment generates longitudinal outcomes data.
It belongs to the health system. It is structured for quality reporting, payer conversations, and clinical research. It improves with every case. The longer PERIOME is deployed, the more institutional value it generates.
PERIOME is not a product placement. It is an embedded clinical program.
The more deeply it is integrated — into the pre-anesthesia workflow, the ERAS protocol, the discharge process — the harder it becomes to remove and the more value it generates. It is designed to be irreplaceable.
Deploy the perioperative infrastructure your surgical program has been missing.
PERIOME is in early institutional deployment. We partner with health systems and surgical programs that recognize the perioperative window as the highest-leverage, least-optimized opportunity in surgical care. Every deployment is designed directly with the PERIOME founding team — not handed off, not templated.