Investor overview

A $200 billion surgical ecosystem. No readiness infrastructure.

Fifty million surgical procedures happen annually in the United States. Almost none of those patients receive structured physiologic preparation for what surgery asks of the human body. PERIOME is building the commercial infrastructure for that discipline.

Why now

Three converging forces.

The perioperative preparation gap has existed for decades. Three forces make this the moment to build the infrastructure around it.

01

Clinical conviction

The gap was not found in a market analysis. It was observed across thousands of surgical cases by the anesthesiologists who founded the company. Perioperative medicine has matured to the point where the evidence base, institutional receptivity and clinical workforce can support the infrastructure around it.

02

Institutional accountability

CMS TEAM and the broader shift to episode-based payment mean surgical programs are now financially responsible for outcomes the system previously absorbed. That did not create the gap. It created the consequence for ignoring it.

03

Technology enablement

Integrating preparation data, physiologic status and clinical context into a quantified readiness framework requires infrastructure that has only recently become available at scale.

Market figure: $200B+ U.S. surgical care ecosystem. CMS TEAM: 188 markets, mandatory January 2026 through December 2030.

The thesis

Three optimized pillars. The fourth has no owner.

The procedure, the anesthesia and the operating room environment have each been systematically built and operationalized over decades. The physiologic state of the patient moving through that window has not.

The protocol is the entry point. The platform is the destination: the intelligence infrastructure that surgical programs, health systems and payers have never had.

What we are building toward

Entry point first. Infrastructure next.

Each layer generates independent value and compounds with every patient the system prepares.

  1. The protocol

    A physician-formulated preparation protocol, available today, placed at the point of care.

  2. The measure

    Readiness quantified before induction, so preparation can be managed rather than assumed.

  3. The data layer

    Outcomes connected across cases, compounding into evidence no single institution could generate alone.

Forward-looking statements describe intended development, not current capability. Patent pending.

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The standard

Built by people who have stood in that room.

PERIOME was founded by two board-certified anesthesiologists who identified the same gap across thousands of cases.

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A new standard for the oldest promise in medicine: that the patient comes first.