Timing
Seven days either side
Taken once daily beginning seven days pre-operatively and continuing through seven days post-operatively. On the day of surgery, patients follow their surgical team's fasting and clear-liquid guidance.
For clinicians
You know what a prepared patient looks like. Most don't arrive that way.
The variables that shape induction and recovery are addressable in the weeks before the incision, and measurable in the weeks after it. What has never existed is the clinical system to do either at scale.
The ERAS gap
ERAS tells the clinical team what to do. PERIOME prepares the patient to respond to it.
ERAS is the most evidence-supported framework in modern perioperative medicine. Every ERAS guideline, though, assumes the patient arrives physiologically ready.
PERIOME addresses the window ERAS does not reach: the days before admission, when metabolic, hydration and micronutrient status can still be changed.
At the point of care
Recommended at the pre-anesthesia evaluation.
No prescription, no portal integration and no new operational layer required for basic recommendation and patient use.
Safety profile
Screened for the window
Every ingredient was screened against antiplatelet, anticoagulant, glycemic and hemodynamic interaction risk, and reviewed for compatibility with commonly used anesthetic agents.
Workflow
One dose, one course
A single daily dose across one full course. Nothing to prescribe, nothing to integrate, and nothing added to the pre-anesthesia visit beyond a recommendation.
Structure and function only. PERIOME makes no claim to prevent, treat or reduce surgical complications.
Clinical framework
What PERIOME addresses.
The protocol targets six physiologic domains relevant to the surgical window: hydration and electrolytes; metabolic and recovery capacity; neurocognitive resilience; immune and inflammatory resilience; GI integrity and microbiome; micronutrient foundation.
Each was selected for a perioperative-specific mechanism rather than general wellness, and none overlap with standard ERAS pharmacologic protocols.
Full domain and formulation detailWhere it goes next
Readiness, resolved to the physiology you manage.
The Perioperative Resilience Index is built to resolve into the six physiologic domains, anesthetic pharmacogenomics and the perioperative labs that matter, so a clinician can see where a patient stands before induction. In development; illustrative only, and not a diagnostic.
-
Before induction
A composite readiness measure and the six domains it resolves into.
-
Pharmacogenomics
How this patient metabolizes the agents they are about to receive.
-
After discharge
Recovery followed against the patient's own preoperative baseline.
Care is delivered by surgeons, anesthesiologists, nurses and perioperative teams. PERIOME's role is to make the patient better understood, better prepared, and connected throughout.
The Perioperative Health Council
The clinicians defining this discipline are the ones practising it.
The Council is the working body establishing what perioperative health measures, what evidence standard it holds itself to, and what it may claim. It spans anesthesiology, surgery, nursing, nutrition science, pharmacy and health system operations.
It is working membership, not a masthead, and its conclusions are published. If you carry patients through this window, your discipline belongs in the room.
Join the CouncilPhysician-founded
Built from inside the operating room.
PERIOME was founded by two board-certified anesthesiologists who spent their careers receiving patients no one had prepared.
Research and clinical collaborationBuilt from inside the operating room.